Hereditary Cancer in Clinical Practice

Editors-in-Chief

Jan Lubinski, Pomeranian Medical University
Rodney J. Scott, University of Newcastle
Rolf Sijmons, University Medical Center Groningen

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The official journal of the International Hereditary Cancer Center and published under the auspices of the International Union Against Cancer

Articles

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Case report

Novel germline MSH2 mutation in Lynch syndrome patient surviving multiple cancers

Janavicius R and Elsakov P Hereditary Cancer in Clinical Practice 2012, 10:1 (10 January 2012)
Research

Prevalence of the BRCA1 founder mutation c.5266dup in Brazilian individuals at-risk for the Hereditary Breast and Ovarian Cancer Syndrome

Ewald IP, Izetti PR, Vargas FR, Moreira MAM, Moreira AS, Moreira-Filho CA, Cunha DR, Hamaguchi S et al. Hereditary Cancer in Clinical Practice 2011, 9:12 (20 December 2011)
Research

Screening for ovarian cancer in women with varying levels of risk, using annual tests, results in high recall for repeat screening tests

Nobbenhuis MAE, Bancroft E, Moskovic E, Lennard F, Pharoah P, Jacobs I, Ward A, Barton DPJ et al. Hereditary Cancer in Clinical Practice 2011, 9:11 (23 November 2011)
Research

Prevalence of BRCA1 and BRCA2 mutations in unselected breast cancer patients from Greece

Koumpis C, Dimitrakakis C, Antsaklis A, Royer R, Zhang S, Narod SA and Kotsopoulos J Hereditary Cancer in Clinical Practice 2011, 9:10 (15 November 2011)
Research

Molecular study of the perforin gene in familial hematological malignancies

El Abed R, Bourdon V, Voskoboinik I, Omri H, Youssef YB, Laatiri MA, Huiart L, Eisinger F et al. Hereditary Cancer in Clinical Practice 2011, 9:9 (21 September 2011)
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Aims & scope

Hereditary Cancer in Clinical Practice is an open access journal that publishes articles of interest for the cancer genetics community and serves as a discussion forum for the development of appropriate healthcare strategies.

Editors' profiles

Profile of Professor Jan Lubinski

Quote

“Hereditary Cancer in Clinical Practice publishes articles on advanced and unique concepts within hereditary cancer, aided by editors with experience of both research and clinical practice relating to populations with DNA testing based on founder mutations. This allows us to understand the necessary improvements in genetic counselling, the value of population screenings as well as the unique achievements in chemotherapy and chemoprevention.”

Profile of Professor Rodney J Scott

Quote

“Anyone interested in hereditary predispositions to cancer should have access to Hereditary Cancer in Clinical Practice. This is an open access journal that addresses the needs of all physicians and medical scientists interested in genetics through to psycho-social issues related to inherited predispositions to cancer.”

Profile of Dr Rolf Sijmons

Quote

“A family history of cancer is a powerful indicator of cancer risk. Many hundreds of familial cancer syndromes with high penetrant mutations exist. In addition, combinations of low-penetrant germline mutations may add up to significant cancer risks in individuals. The practical aspects of recognizing familial cancer syndromes, studying the inherited causes of cancer and researching the medical management of patients and families with high genetic risks are the topics of our journal. Publishing in an open access format supports the spread of knowledge on hereditary cancer within the professional community.”