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	1. 2908 Accesses	Case report Familial Multiple Myeloma: Report on Two Families and Discussion of Screening Options Erica H Gerkes, Mirjam M de Jong, Rolf H Sijmons, Edo Vellenga Hereditary Cancer in Clinical Practice 2007, 5:72-78 (15 June 2007) Abstract \| Full text \| PDF \| PubMed
	2. 2860 Accesses	Research Cancer risk in MLH1, MSH2 and MSH6 mutation carriers; different risk profiles may influence clinical management Dewkoemar Ramsoekh, Anja Wagner, Monique E van Leerdam, Dennis Dooijes, Carli MJ Tops, Ewout W Steyerberg, Ernst J Kuipers Hereditary Cancer in Clinical Practice 2009, 7:17 (23 December 2009) Abstract \| Full text \| PDF \| PubMed
	3. 2317 Accesses	Case report Unusual presentation of Lynch Syndrome Veronica PCC Yu, Marco Novelli, Stewart J Payne, Sam Fisher, Rebecca A Barnetson, Ian M Frayling, Ann Barrett, David Goudie, Audrey Ardern-Jones, Ros Eeles, Susan Shanley Hereditary Cancer in Clinical Practice 2009, 7:12 (3 June 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	4. 2287 Accesses	Review Drug therapy for hereditary cancers Evgeny N Imyanitov, Vladimir M Moiseyenko Hereditary Cancer in Clinical Practice 2011, 9:5 (6 August 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	5. 2126 Accesses	Research MSH6 and PMS2 mutation positive Australian Lynch syndrome families: novel mutations, cancer risk and age of diagnosis of colorectal cancer Bente A Talseth-Palmer, Mary McPhillips, Claire Groombridge, Allan Spigelman, Rodney J Scott Hereditary Cancer in Clinical Practice 2010, 8:5 (21 May 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The Australian authors identified 26 different MSH6 and 4 different PMS2 mutations in 35 Lynch syndrome families studied. For MSH6 mutation carriers, the estimated cumulative risk of CRC at age 70 years was 61% (similar in males and females) and 65% for endometrial cancer. The risk of developing CRC was found to be different between males and females at age 50 years: 34% for males and 21% for females.
	6. 2093 Accesses	Short report Encyclopaedia of tumour-associated familial disorders. Part I: from AIMAH to CHIME syndrome Rolf H Sijmons Hereditary Cancer in Clinical Practice 2008, 6:22-57 (15 March 2008) Abstract \| Full text \| PDF \| PubMed
	7. 2042 Accesses	Research Prevalance of BRCA1 and BRCA2 mutations in familial breast cancer patients in Lebanon Nadine Jalkh, Jinane Nassar-Slaba, Eliane Chouery, Nabiha Salem, Nancy Uhrchammer, Lisa Golmard, Domique Stoppa-Lyonnet, Yves-Jean Bignon, André Mégarbané Hereditary Cancer in Clinical Practice 2012, 10:7 (19 June 2012) Abstract \| Full text \| PDF \| PubMed
	8. 1996 Accesses	Research Chronic lymphocytic leukaemia: clinical-aetiological findings in 66 patients and their families Walter Weber, Patrick F Maurer, Jacqueline Estoppey, Marcel Zwahlen Hereditary Cancer in Clinical Practice 2007, 5:210-212 (15 December 2007) Abstract \| Full text \| PDF \| PubMed
	9. 1964 Accesses	Review Familial paragangliomas CJM Lips, EGWM Lentjes, JWM Höppener, RB Luijt, FL Moll Hereditary Cancer in Clinical Practice 2006, 4:169-176 (15 October 2006) Abstract \| Full text \| PDF \| PubMed
	10. 1912 Accesses	Review Familial gastric cancer: detection of a hereditary cause helps to understand its etiology Ingrid P Vogelaar, Rachel S van der Post, Tanya M Bisseling, J Han JM van Krieken, Marjolijn JL Ligtenberg, Nicoline Hoogerbrugge Hereditary Cancer in Clinical Practice 2012, 10:18 (12 December 2012) Abstract \| Full text \| PDF \| PubMed
	11. 1852 Accesses	Research Family perspectives in lynch syndrome becoming a family at risk, patterns of communication and influence on relations Katarina Bartuma, Mef Nilbert, Christina Carlsson Hereditary Cancer in Clinical Practice 2012, 10:6 (25 May 2012) Abstract \| Full text \| PDF \| PubMed
	12. 1843 Accesses	Research Factors associated with testicular self-examination among unaffected men from multiple-case testicular cancer families Susan T Vadaparampil, Richard P Moser, Jennifer Loud, June A Peters, Mark H Greene, Larissa Korde Hereditary Cancer in Clinical Practice 2009, 7:11 (29 May 2009) Abstract \| Full text \| PDF \| PubMed
	13. 1810 Accesses	Research Penetrance of HNPCC-related cancers in a retrolective cohort of 12 large Newfoundland families carrying a MSH2 founder mutation: an evaluation using modified segregation models Karen A Kopciuk, Yun-Hee Choi, Elena Parkhomenko, Patrick Parfrey, John McLaughlin, Jane Green, Laurent Briollais Hereditary Cancer in Clinical Practice 2009, 7:16 (28 October 2009) Abstract \| Full text \| PDF \| PubMed
	14. 1771 Accesses	Case report Primary appendiceal mucinous adenocarcinoma in two first-degree relatives: case report and review Adrianne R Racek, Kari G Rabe, Myra J Wick, Apostolos Psychogios, Noralane M Lindor Hereditary Cancer in Clinical Practice 2011, 9:1 (4 May 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Published accounts of familial instances of primary appendiceal tumors are strikingly rare. The authors report two siblings who both developed primary mucinous adenocarcinomas, and found one additional affected sib-pair among 316 cases of primary appendiceal cancer of any histologic type recorded in the Mayo clinic. Although these cases may be coincidental, an exceedingly rare predisposition syndrome cannot be ruled out.
	15. 1746 Accesses	Meeting abstract BRCA1 mutation- oncological treatment- reconstructive surgery of the breast- pregnancy: diagnostic and therapeutic procedures in a 28 year old patient diagnosed with a tumor in the left breast with a BRCA1 mutation Ewa Kilar Hereditary Cancer in Clinical Practice 2012, 10(Suppl 1):A9 (12 January 2012) Full text \| PDF
	16. 1706 Accesses	Case report Challenges in the management of a patient with Cowden syndrome: case report and literature review Inga Melbārde-Gorkuša, Arvīds Irmejs, Dace Bērziņa, Ilze Štrumfa, Arnis Āboliņš, Andris Gardovskis, Signe Subatniece, Genādijs Trofimovičs, Jānis Gardovskis, Edvīns Miklaševičs Hereditary Cancer in Clinical Practice 2012, 10:5 (14 April 2012) Abstract \| Full text \| PDF \| PubMed
	17. 1689 Accesses	Review Determining the functional significance of mismatch repair gene missense variants using biochemical and cellular assays Christopher D Heinen, LJ Rasmussen Hereditary Cancer in Clinical Practice 2012, 10:9 (23 July 2012) Abstract \| Full text \| PDF \| PubMed
	18. 1638 Accesses	Research BRAF mutations in thyroid tumors from an ethnically diverse group Hans-Juergen Schulten, Sherine Salama, Zuhoor Al-Mansouri, Reem Alotibi, Khalid Al-Ghamdi, Osman Al-Hamour, Hassan Sayadi, Hosam Al-Aradati, Adel Al-Johari, Etimad Huwait, Mamdooh Gari, Mohammed Al-Qahtani, Jaudah Al-Maghrabi Hereditary Cancer in Clinical Practice 2012, 10:10 (27 August 2012) Abstract \| Full text \| PDF \| PubMed
	19. 1638 Accesses	Research Cancer and Lhermitte-Duclos disease are common in Cowden syndrome patients Douglas L Riegert-Johnson, Ferga C Gleeson, Maegan Roberts, Krysta Tholen, Lauren Youngborg, Melvin Bullock, Lisa A Boardman Hereditary Cancer in Clinical Practice 2010, 8:6 (17 June 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary In this study from the Mayo clinic, a total of 211 Cowden syndrome patients were included. The cumulative lifetime risks were 89% for any cancer diagnosis, breast cancer [female] 81%, Lhermitte-Duclos disease 32%, thyroid cancer 21%, endometrial cancer 19%, and renal cancer 15%. A previously unreported increased lifetime risk for colorectal cancer was identified (16%, 95% CI = 8%-24%). Male CS patients had fewer cancers diagnosed than female patients and often had cancers not classically associated with CS. Seven percent of breast and thyroid cancers occurred in patients who were younger than the recommended age to commence radiographic cancer screening!
	20. 1617 Accesses	Research Familial Cervical Cancer: Case Reports, Review and Clinical Implications Margreet Zoodsma, Rolf H Sijmons, Elisabeth GE de Vries, Ate Zee Hereditary Cancer in Clinical Practice 2004, 2:99-105 (15 May 2004) Abstract \| Full text \| PDF \| PubMed
	21. 1590 Accesses	Review Genetic Screening for Familial Gastric Cancer Carla Oliveira, Gianpaolo Suriano, Paulo Ferreira, Paulo Canedo, Pardeep Kaurah, Rita Mateus, Ana Ferreira, António C Ferreira, Maria Oliveira, Céu Figueiredo, Fátima Carneiro, Gisela Keller, David Huntsman, José Machado, Raquel Seruca Hereditary Cancer in Clinical Practice 2004, 2:51-64 (15 May 2004) Abstract \| Full text \| PDF \| PubMed
	22. 1581 Accesses	Research A Pilot study of the Sharing Risk Information Tool (ShaRIT) for Families with Hereditary Breast and Ovarian Cancer Syndrome Ani Kardashian, Julia Fehniger, Jennifer Creasman, Eleanor Cheung, Mary Beattie Hereditary Cancer in Clinical Practice 2012, 10:4 (12 April 2012) Abstract \| Full text \| PDF \| PubMed
	23. 1581 Accesses	Research Factors influencing receptivity to future screening options for pancreatic cancer in those with and without pancreatic cancer family history Carmen Breitkopf, Pamela S Sinicrope, Kari G Rabe, Tabetha A Brockman, Christi A Patten, Robert R McWilliams, Shawna Ehlers, Gloria M Petersen Hereditary Cancer in Clinical Practice 2012, 10:8 (27 June 2012) Abstract \| Full text \| PDF \| PubMed
	24. 1580 Accesses	Research Factors Influencing Cancer Risk Perception in High Risk Populations: A Systematic Review Jon C Tilburt, Katherine M James, Pamela S Sinicrope, David T Eton, Brian A Costello, Jantey Carey, Melanie A Lane, Shawna L Ehlers, Patricia J Erwin, Katherine E Nowakowski, Mohammad H Murad Hereditary Cancer in Clinical Practice 2011, 9:2 (19 May 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Patients at higher than average risk of heritable cancer may process risk information differently than the general population. However, little is known about clinical, demographic, or psychosocial predictors that may impact risk perception in these groups. The authors from the Mayo clinic searched literature databases for published research on these topics. Family history of cancer, previous prophylactic tests and treatments, and younger age have been shown to be associated with cancer risk perception. In addition, beliefs about the preventability and severity of cancer, personality factors such as "monitoring" personality, the ability to process numerical information, as well as distress/worry also were associated with cancer risk perception. Few studies addressed non-breast cancer or risk perception in specific demographic groups (e.g. elderly or minority groups) and few employed theory-driven analytic strategies to decipher interrelationships of factors. Clearly, there is need for additional studies.
	25. 1504 Accesses	Review DNA and RNA analyses in detection of genetic predisposition to cancer Grzegorz Kurzawski, Dagmara Dymerska, Pablo Serrano-Fernández, Joanna Trubicka, Bartłomiej Masojć, Anna Jakubowska, Rodney J Scott Hereditary Cancer in Clinical Practice 2012, 10:17 (4 December 2012) Abstract \| Full text \| PDF \| PubMed