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	1. 550 Accesses	Research Penetrance of HNPCC-related cancers in a retrolective cohort of 12 large Newfoundland families carrying a MSH2 founder mutation: an evaluation using modified segregation models Karen A Kopciuk, Yun-Hee Choi, Elena Parkhomenko, Patrick Parfrey, John McLaughlin, Jane Green, Laurent Briollais Hereditary Cancer in Clinical Practice 2009, 7:16 (28 October 2009) Abstract \| Full text \| PDF \| PubMed
	2. 321 Accesses	Review Systemic treatment for hereditary cancers: a 2012 update Evgeny N Imyanitov, Tomasz Byrski Hereditary Cancer in Clinical Practice 2013, 11:2 (1 April 2013) Abstract \| Full text \| PDF \| PubMed
	3. 308 Accesses	Short report Encyclopaedia of tumour-associated familial disorders. Part I: from AIMAH to CHIME syndrome Rolf H Sijmons Hereditary Cancer in Clinical Practice 2008, 6:22-57 (15 March 2008) Abstract \| Full text \| PDF \| PubMed
	4. 307 Accesses	Review Familial gastric cancer: detection of a hereditary cause helps to understand its etiology Ingrid P Vogelaar, Rachel S van der Post, Tanya M Bisseling, J Han JM van Krieken, Marjolijn JL Ligtenberg, Nicoline Hoogerbrugge Hereditary Cancer in Clinical Practice 2012, 10:18 (12 December 2012) Abstract \| Full text \| PDF \| PubMed
	5. 259 Accesses	Research Cancer risk in MLH1, MSH2 and MSH6 mutation carriers; different risk profiles may influence clinical management Dewkoemar Ramsoekh, Anja Wagner, Monique E van Leerdam, Dennis Dooijes, Carli MJ Tops, Ewout W Steyerberg, Ernst J Kuipers Hereditary Cancer in Clinical Practice 2009, 7:17 (23 December 2009) Abstract \| Full text \| PDF \| PubMed
	6. 240 Accesses	Case report Familial Multiple Myeloma: Report on Two Families and Discussion of Screening Options Erica H Gerkes, Mirjam M de Jong, Rolf H Sijmons, Edo Vellenga Hereditary Cancer in Clinical Practice 2007, 5:72-78 (15 June 2007) Abstract \| Full text \| PDF \| PubMed
	7. 228 Accesses	Research Chemokine Ligand 5 (CCL5) and chemokine receptor (CCR5) genetic variants and prostate cancer risk among men of African Descent: a case-control study LaCreis R Kidd, Dominique Z Jones, Erica N Rogers, Nayla C Kidd, Sydney Beache, James E Rudd, Camille Ragin, Maria Jackson, Norma McFarlane-Anderson, Marshall Tulloch-Reid, Seian Morrison, Guy N Brock, Shirish S Barve, Kevin S Kimbro Hereditary Cancer in Clinical Practice 2012, 10:16 (20 November 2012) Abstract \| Full text \| PDF \| PubMed
	8. 226 Accesses	Case report Unusual presentation of Lynch Syndrome Veronica PCC Yu, Marco Novelli, Stewart J Payne, Sam Fisher, Rebecca A Barnetson, Ian M Frayling, Ann Barrett, David Goudie, Audrey Ardern-Jones, Ros Eeles, Susan Shanley Hereditary Cancer in Clinical Practice 2009, 7:12 (3 June 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	9. 221 Accesses	Review Drug therapy for hereditary cancers Evgeny N Imyanitov, Vladimir M Moiseyenko Hereditary Cancer in Clinical Practice 2011, 9:5 (6 August 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	10. 218 Accesses	Review DNA and RNA analyses in detection of genetic predisposition to cancer Grzegorz Kurzawski, Dagmara Dymerska, Pablo Serrano-Fernández, Joanna Trubicka, Bartłomiej Masojć, Anna Jakubowska, Rodney J Scott Hereditary Cancer in Clinical Practice 2012, 10:17 (4 December 2012) Abstract \| Full text \| PDF \| PubMed
	11. 213 Accesses	Research Prevalance of BRCA1 and BRCA2 mutations in familial breast cancer patients in Lebanon Nadine Jalkh, Jinane Nassar-Slaba, Eliane Chouery, Nabiha Salem, Nancy Uhrchammer, Lisa Golmard, Domique Stoppa-Lyonnet, Yves-Jean Bignon, André Mégarbané Hereditary Cancer in Clinical Practice 2012, 10:7 (19 June 2012) Abstract \| Full text \| PDF \| PubMed
	12. 190 Accesses	Meeting abstract BRCA1 mutation- oncological treatment- reconstructive surgery of the breast- pregnancy: diagnostic and therapeutic procedures in a 28 year old patient diagnosed with a tumor in the left breast with a BRCA1 mutation Ewa Kilar Hereditary Cancer in Clinical Practice 2012, 10(Suppl 1):A9 (12 January 2012) Full text \| PDF
	13. 194 Accesses	Research MSH6 and PMS2 mutation positive Australian Lynch syndrome families: novel mutations, cancer risk and age of diagnosis of colorectal cancer Bente A Talseth-Palmer, Mary McPhillips, Claire Groombridge, Allan Spigelman, Rodney J Scott Hereditary Cancer in Clinical Practice 2010, 8:5 (21 May 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The Australian authors identified 26 different MSH6 and 4 different PMS2 mutations in 35 Lynch syndrome families studied. For MSH6 mutation carriers, the estimated cumulative risk of CRC at age 70 years was 61% (similar in males and females) and 65% for endometrial cancer. The risk of developing CRC was found to be different between males and females at age 50 years: 34% for males and 21% for females.
	14. 185 Accesses	Research Family perspectives in lynch syndrome becoming a family at risk, patterns of communication and influence on relations Katarina Bartuma, Mef Nilbert, Christina Carlsson Hereditary Cancer in Clinical Practice 2012, 10:6 (25 May 2012) Abstract \| Full text \| PDF \| PubMed
	15. 181 Accesses	Review Genetic Screening for Familial Gastric Cancer Carla Oliveira, Gianpaolo Suriano, Paulo Ferreira, Paulo Canedo, Pardeep Kaurah, Rita Mateus, Ana Ferreira, António C Ferreira, Maria Oliveira, Céu Figueiredo, Fátima Carneiro, Gisela Keller, David Huntsman, José Machado, Raquel Seruca Hereditary Cancer in Clinical Practice 2004, 2:51-64 (15 May 2004) Abstract \| Full text \| PDF \| PubMed
	16. 172 Accesses	Review A short guide to hereditary diffuse gastric cancer Parry Guilford, Vanessa Blair, Helen More, Bostjan Humar Hereditary Cancer in Clinical Practice 2007, 5:183-194 (15 December 2007) Abstract \| Full text \| PDF \| PubMed
	17. 172 Accesses	Review Familial paragangliomas CJM Lips, EGWM Lentjes, JWM Höppener, RB Luijt, FL Moll Hereditary Cancer in Clinical Practice 2006, 4:169-176 (15 October 2006) Abstract \| Full text \| PDF \| PubMed
	18. 166 Accesses	Case report Diagnostic and pathogenetic role of café-au-lait macules in nevoid basal cell carcinoma syndrome Giovanni Ponti, Aldo Tomasi, Lorenza Pastorino, Cristel Ruini, Carmelo Guarneri, Victor Mandel, Stefania Seidenari, Giovanni Pellacani Hereditary Cancer in Clinical Practice 2012, 10:15 (29 October 2012) Abstract \| Full text \| PDF \| PubMed
	19. 162 Accesses	Research Factors influencing receptivity to future screening options for pancreatic cancer in those with and without pancreatic cancer family history Carmen Breitkopf, Pamela S Sinicrope, Kari G Rabe, Tabetha A Brockman, Christi A Patten, Robert R McWilliams, Shawna Ehlers, Gloria M Petersen Hereditary Cancer in Clinical Practice 2012, 10:8 (27 June 2012) Abstract \| Full text \| PDF \| PubMed
	20. 162 Accesses	Case report Should extragonadal germ cell tumors be included in studies of families with testicular germ cell tumors? Rodrigo Santa Cruz Guindalini, Edite Paulo de Oliveira, Marina Cavalcanto Moroja Silvino, Paulo Marcelo Hoff, Bernardo Garicochea Hereditary Cancer in Clinical Practice 2013, 11:1 (4 March 2013) Abstract \| Full text \| PDF \| PubMed
	21. 156 Accesses	Research A Pilot study of the Sharing Risk Information Tool (ShaRIT) for Families with Hereditary Breast and Ovarian Cancer Syndrome Ani Kardashian, Julia Fehniger, Jennifer Creasman, Eleanor Cheung, Mary Beattie Hereditary Cancer in Clinical Practice 2012, 10:4 (12 April 2012) Abstract \| Full text \| PDF \| PubMed
	22. 155 Accesses	Case report Primary appendiceal mucinous adenocarcinoma in two first-degree relatives: case report and review Adrianne R Racek, Kari G Rabe, Myra J Wick, Apostolos Psychogios, Noralane M Lindor Hereditary Cancer in Clinical Practice 2011, 9:1 (4 May 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Published accounts of familial instances of primary appendiceal tumors are strikingly rare. The authors report two siblings who both developed primary mucinous adenocarcinomas, and found one additional affected sib-pair among 316 cases of primary appendiceal cancer of any histologic type recorded in the Mayo clinic. Although these cases may be coincidental, an exceedingly rare predisposition syndrome cannot be ruled out.
	23. 154 Accesses	Research Prevalence of BRCA1 and BRCA2 mutations in unselected breast cancer patients from Greece Chrissovaladis Koumpis, Constantine Dimitrakakis, Aris Antsaklis, Robert Royer, Shiyu Zhang, Steven A Narod, Joanne Kotsopoulos Hereditary Cancer in Clinical Practice 2011, 9:10 (15 November 2011) Abstract \| Full text \| PDF \| PubMed
	24. 154 Accesses	Research Lynch syndrome: barriers to and facilitators of screening and disease management Kathy E Watkins, Christine Y Way, Jacqueline J Fiander, Robert J Meadus, Mary Esplen, Jane S Green, Valerie C Ludlow, Holly A Etchegary, Patrick S Parfrey Hereditary Cancer in Clinical Practice 2011, 9:8 (7 September 2011) Abstract \| Full text \| PDF \| PubMed
	25. 152 Accesses	Research Cancer and Lhermitte-Duclos disease are common in Cowden syndrome patients Douglas L Riegert-Johnson, Ferga C Gleeson, Maegan Roberts, Krysta Tholen, Lauren Youngborg, Melvin Bullock, Lisa A Boardman Hereditary Cancer in Clinical Practice 2010, 8:6 (17 June 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary In this study from the Mayo clinic, a total of 211 Cowden syndrome patients were included. The cumulative lifetime risks were 89% for any cancer diagnosis, breast cancer [female] 81%, Lhermitte-Duclos disease 32%, thyroid cancer 21%, endometrial cancer 19%, and renal cancer 15%. A previously unreported increased lifetime risk for colorectal cancer was identified (16%, 95% CI = 8%-24%). Male CS patients had fewer cancers diagnosed than female patients and often had cancers not classically associated with CS. Seven percent of breast and thyroid cancers occurred in patients who were younger than the recommended age to commence radiographic cancer screening!