Table 4

Estimated hazard ratios of colorectal cancer risk at ages 30, 50 and 70 (and corresponding 95% confidence interval) in gene mutation carriers (any MMR, MLH1, MSH2) compared with that in the general population, based on the segregation analysis.

Mutation

Age 30

Age 50

Age 70

Any MMR

10.5 (2.5, 46.9)

8.8 (2.3, 40.1)

5.5 (1.8, 25.0)

MLH1

5.5 (0.8, 53.6)

6.5 (1.4, 41.8)

5.1 (1.3, 26.9)

MSH2

13.1 (0.3, 78.8)

9.3 (0.3, 44.4)

5.4 (0.3, 24.5)

Choi et al. Hereditary Cancer in Clinical Practice 2009 7:14   doi:10.1186/1897-4287-7-14