|
Frequency of identified panel of markers in all breast cancers diagnosed at age above 50 and controls [9] |
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| Gene/Marker |
Cancer |
Controls |
|
|
||
| BRCA1 |
2.1% (14/667) |
0% (0/667) |
|
|
||
| CHEK2 |
11% (72/653) |
4.8% (32/667) |
|
|
||
| p53 |
11% (64/581) |
5.4% (34/635) |
|
|
||
| TNR |
55.9% (289/517) |
45.3% (272/601) |
|
|
||
| FGFR - nAA |
68.9% (157/228) |
60.8% (200/329) |
|
|
||
| BRCA2 |
5.6% (4/71) |
2.3% (3/129) |
|
|
||
| XPD - CC/AA |
13.4% (9/67) |
6.3% (8/126) |
|
|
||
| NOD2 |
13.8% (8/58) |
6.8% (8/118) |
|
|
||
| XPD - GG |
48% (24/50) |
35.5% (39/110) |
|
|
||
| Any marker |
96.1% (641/667) |
89.4% (596/667) |
|
|
||
| Statistic |
P = 2.4 × 10-6 |
|
Dębniak and Lubiński Hereditary Cancer in Clinical Practice 2008 6:69 doi:10.1186/1897-4287-6-2-69 |
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