|
Frequency of identified panel of markers in unselected breast Cancers and controls [9] |
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| Gene/Marker |
Cancer |
Controls |
|
|
||
| BRCA1 |
2.7% (26/977) |
0% (0/977) |
|
|
||
| CHEK2 |
11.9% (113/951) |
6% (59/977) |
|
|
||
| p53 |
10.1% (85/838) |
5.7% (52/918) |
|
|
||
| TNR |
55.6% (419/753) |
45.8% (397/866) |
|
|
||
| FGFR - GG |
18.3% (61/334) |
13.9% (65/469) |
|
|
||
| CDKN2A |
7% (19/273) |
5.4% (22/404) |
|
|
||
| XPD - GG |
41% (104/254) |
36.4% (139/382) |
|
|
||
| XPD - CC/AA |
17.3% (26/150) |
14% (34/243) |
|
|
||
| BRCA2 |
7.3% (9/124) |
4.8% (10/209) |
|
|
||
| XPD - AA |
20% (23/115) |
18.6% (37/199) |
|
|
||
| Any marker |
90.6% (885/977) |
83.4% (815/977) |
|
|
||
| Statistic |
P = 3 × 10-6 |
|
Dębniak and Lubiński Hereditary Cancer in Clinical Practice 2008 6:69 doi:10.1186/1897-4287-6-2-69 |
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