Table 9

The effect of tamoxifen on the risk of contralateral breast cancer by menopausal status (univariate analysis)

Parameters

n

OR

95% CI

p

Both cancers premenopausal

86

0.31

0.11-0.82

0.02

A. All carriers:

259

0.44

0.27-0.65

0.0009

- Pre- and postmenopausal

114

0.54

0.27-1.05

0.07

- Both cancers postmenopausal

37

0.33

0.11-1.01

0.05

B. Natural menopause only:

- Pre- and postmenopausal

22

0.13

0.02-1.10

0.06

- Both cancers postmenopausal

13

0.45

0.09-2.37

0.34

CI - confidence interval; n - number of cases; OR - odds ratio; p - statistical significance.

Gronwald Hereditary Cancer in Clinical Practice 2007 5:3   doi:10.1186/1897-4287-5-1-3