Table 1

Association of the NOD2 3020insC mutation and selected types of cancer

Site

Number tested

Number positive

Prevalence of 3020insC (%)

Odds ratio

p-value

bladder

172

18

10.5

1.5

0.13

breast

462

37

8.0

1.1

0.62

with DCIS

126

18

14.3

2.1

0.009

without DCIS

336

19

5.7

0.76

0.30

colon

255

31

12.2

1.8

0.01

kidney

245

8

3.2

0.4

0.02

larynx

223

23

10.3

1.5

0.11

lung

258

30

11.6

1.7

0.03

melanoma

198

10

5.1

0.7

0.31

ovary

317

35

11.0

1.6

0.03

pancreas

127

6

4.7

0.6

0.37

prostate

298

17

5.7

0.76

0.40

stomach

213

20

9.4

1.3

0.27

thyroid

82

8

9.8

1.4

0.39

controls 1910

140

7.3

Lubiński et al. Hereditary Cancer in Clinical Practice 2005 3:59   doi:10.1186/1897-4287-3-2-59