Table 1 |
|||||||
| Demographic and BRAF mutational survey in thyroid lesions | |||||||
| Thyroid lesion | Number | Age at diagnosis (years, SD) | Female/male ratio | Family history | BRAF status1 | ||
| neg | pos | wt | mut | ||||
| Thyroiditis | 10 | 36.7 ±12.5 | 10:0 | 5 | 2 | 10 | 0 |
| Goiter | 46 | 41.9 ±11.4 | 2.3:1 | 19 | 5 | 46 | 0 |
| Hyperplastic | 18 | 34.4 ±12.5 | 8:1 | 8 | 0 | 18 | 0 |
| FA | 69 | 38.4 ±13.1 | 3:1 | 11 | 2 | 68 | 1 T599del |
| FTC | 17 | 40.4 ±16.7 | 3.3:1 | 2 | 2 | 16 | 1 K601E |
| PTC | 115 | 41.1 ±15.5 | 2.3:1 | 27 | 4 | 43 | 1 T599insT, 70 V600E, 1 K601E |
| FVPTC | 42 | 40.5 ±15.6 | 5:1 | 9 | 4 | 35 | 6 V600E, 1 K601E |
| Micro PTC | 56 | 36.4 ±13.5 | 6:1 | 10 | 4 | 46 | 10 V600E |
| Non-WDTC | 8 | 59.0 ±10.1 | 7:1 | 1 | 1 | 7 | 1 V600E |
1Wt, BRAF wild type; mut, BRAF mutated.
Schulten et al. Hereditary Cancer in Clinical Practice 2012 10:10 doi:10.1186/1897-4287-10-10
